European Society Intensive Care Medicine и Society Critical Care Medicine: 6 ключевых положений по ведению пациентов с сепсисом. Куда идем дальше?

Цель: анализ обоснованности рекомендаций специального научного комитета European Society Intensive Care Medicine (ESICM) и Society Critical Care Medicine (SCCM), касающихся наиболее важных положений по ведению пациентов c сепсисом и септическим шоком, с выделением предикторов долгосрочной нуждаемости в оказании медицинской помощи и летальности.

Материалы и методы. Выполнен анализ источников литературы, на основании которых экспертами по ведению больных сепсисом выделены ключевые положения рекомендаций.

Результаты. Акцентировано внимание на шести положениях: эмпирическая комбинированная антибиотикотерапия, индивидуальная по объему инфузия, быстрая диагностика инфекции, оценка органно-системной дисфункции, выделение предикторов долгосрочной нуждаемости в оказании медицинской помощи и летальности, попытки внедрения и перспективы точной/персонализированной медицины. Показано, что значения шкалы SOFA, ЧСС, сист.АД, содержание лактата и альбумина должны отражать сбалансированность групп по данным параметрам. Молекулярная классификация больных с сепсисом, предусматривающая наличие различных эндотипов, создает условия для лучшей селекции пациентов в клинических исследованиях.

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