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NEUROGENIC PULMONARY EDEMA

https://doi.org/10.21292/2078-5658-2018-15-1-55-62

Abstract

Neurogenic pulmonary edema is one of the complications of acute cerebral diseases and traumas and it is accompanied by severe respiratory failure. It is associated with a high mortality level. There are several theories about neurogenic pulmonary edema development. The theory of the double hit is the most recent causing significant discussion. The theory is based on the pulmonary injury due to systemic inflammatory response when the glial tissue of the injured brain becomes the source of inflammatory mediators. A similar pathogenesis allows considering neurogenic pulmonary edema to be one of the forms of acute respiratory distress syndrome. It has diagnostic criteria common with acute respiratory distress syndrome, which are identified during acute cerebral injury and not associated with the other etiological factors. Currently, there are no effective prevention and treatment of neurogenic pulmonary edema. Support of respiratory exchange through artificial pulmonary ventilation is a major tool used for its management, which is recommended to be performed in compliance with protective ventilation principles. And some particular approaches of the preventive ventilation can be applied only with neuromonitoring.

 

About the Authors

V. I. Shatalov
S.M. Kirov Military Medical Academy
Russian Federation
Candidate of Medical Sciences, Teacher of Anesthesiology and Intensive Care Department


A. V. Schegolev
S.M. Kirov Military Medical Academy
Russian Federation
Doctor of Medical Sciences, Head of Anesthesiology and Intensive Care Department (Head of the Clinic)


A. N. Gritsay
S.M. Kirov Military Medical Academy
Russian Federation
Candidate of Medical Sciences, Senior Teacher of Anesthesiology and Intensive Care Department


V. S. Afonchikov
Dzhanilidze St. Petersburg Research Institute of Emergency Care
Russian Federation
Candidate of Medical Sciences, Deputy Head Doctor for Anesthesiology and Intensive Care, Deputy Head of Anesthesiology and Intensive Care Clinical Center.


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Review

For citations:


Shatalov V.I., Schegolev A.V., Gritsay A.N., Afonchikov V.S. NEUROGENIC PULMONARY EDEMA. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2018;15(1):55-62. (In Russ.) https://doi.org/10.21292/2078-5658-2018-15-1-55-62



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