OXYGEN DELIVERY, GASES AND ACID-BASE BALANCE OF ARTERIAL BLOOD DURING XENON ANESTHESIA OF THE CLOSED CIRCU
https://doi.org/10.21292/2078-5658-2017-14-4-32-37
Abstract
Xenon is an inert gas being very close to an ideal anesthetic. Goal of the study: to evaluate changes in gases and acid-base balance of arterial blood during general xenon anesthesia with the closed circuit and to compare it with general anesthesia with sevoflurane. Methods. The article describes a prospective assessment of anesthesia with expanded hemodynamic monitoring in 50 patients undergoing planned surgery. Based on the main inhalation anesthetic (xenon or sevoflurane) patients were divided into two groups. The monitoring included blood gases and O2 delivery; cardiac output was evaluated through analysis of arterial pressure pulse wave after calibration by transpulmonary thermodilution (PiCCO). Results. Xenon anesthesia did not result in serious disorders of acid-base balance and O2 delivery and compared to sevoflurane the metabolic acidosis was less frequent as well as the need to manage it. Changes in the lactate level provided the evidence that both inhalation anesthetics did not result in serious disorders of tissue perfusion and gas exchange.
About the Authors
A. Yu. Kulikov
St. Petersburg Multi-Field Center (University Clinic of St. Petersburg University), St. Petersburg
Russian Federation
Doctor of Anesthesiology and Intensive Care Department
Russian Federation
Doctor of Anesthesiology and Intensive Care Department
O. V. Kuleshov
St. Petersburg Multi-Field Center (University Clinic of St. Petersburg University), St. Petersburg;
I. I. Mechnikov Northern-Western Medical University, St. Petersburg
Russian Federation
Candidate of Medical Sciences, Head of Anesthesiology and Intensive Care Department
Russian Federation
Candidate of Medical Sciences, Head of Anesthesiology and Intensive Care Department
K. M. Lebedinskiy
I. I. Mechnikov Northern-Western Medical University, St. Petersburg
Russian Federation
Doctor of Medical Sciences, Professor, Head of Vanevsky Anesthesiology and Intensive Care Faculty
Russian Federation
Doctor of Medical Sciences, Professor, Head of Vanevsky Anesthesiology and Intensive Care Faculty
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Review
For citations:
Kulikov A.Yu., Kuleshov O.V., Lebedinskiy K.M. OXYGEN DELIVERY, GASES AND ACID-BASE BALANCE OF ARTERIAL BLOOD DURING XENON ANESTHESIA OF THE CLOSED CIRCU. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2017;14(4):32-37. (In Russ.) https://doi.org/10.21292/2078-5658-2017-14-4-32-37
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