EARLY TARGETED TREATMENT OF SEPTIC SHOCK: RESULTS OF MULTICENTER RETROSPECTIVE STUDY
https://doi.org/10.21292/2078-5658-2015-12-2-14-20
Abstract
Multicenter, retrospective, cohort study was conducted enrolling 727 patients suffering from septic shock as a complication of extensive peritonitis (abdominal sepsis). Patients were treated in eight intensive care departments of eight medical units. Outcomes were compared depending on the applied tactics (using algorithm of early targeted therapy of septic shock in accordance with international recommendations and local approaches typical for a certain unit). It has been found out that the algorithm of early targeted therapy was used unreasonably rearly (in 27% of patients in the study subpopulation). However its application allowed reducing the mortality by 12% and increasing 28-day survival period.
About the Authors
L. L. Plotkin
South Ural State Medical University
Russian Federation
Russian Federation
I. Yu. Smolensky
Road Clinical Hospital, Chelyabinsk
Russian Federation
Russian Federation
N. N. Timchenko
Road Clinical Hospital, Chelyabinsk
Russian Federation
Russian Federation
I. P. Shapko
Regional Hospital, Kostanay
Kazakhstan
Kazakhstan
N. N. Safronova
Chelyabinsk Regional Clinical Hospital no.1
Russian Federation
Russian Federation
A. G. Konashev
Municipal Clinical Hospital no.8, Chelyabinsk
Russian Federation
Russian Federation
I. S. Edelshtein
Chelyabinsk Regional Clinical Hospital no.2
Russian Federation
Russian Federation
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Review
For citations:
Plotkin L.L., Smolensky I.Yu., Timchenko N.N., Shapko I.P., Safronova N.N., Konashev A.G., Edelshtein I.S. EARLY TARGETED TREATMENT OF SEPTIC SHOCK: RESULTS OF MULTICENTER RETROSPECTIVE STUDY. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2015;12(2):14-20. (In Russ.) https://doi.org/10.21292/2078-5658-2015-12-2-14-20
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