Risk factors for early and late unplanned readmissions to the intensive care unit – results of a survey among intensivist
https://doi.org/10.24884/2078-5658-2025-22-1-68-79
Abstract
Introduction. The knowledge and experience of anesthesiologists about predictors of unplanned ICU (intensive care unit) readmission are implemented into practical models for their prevention. However, differences in the time before patient’s ICU readmission make significant adjustments to the possibility of their implementation.
The objective was to analyze intensivist opinions about predictors of early and late unplanned ICU readmissions. Materials and methods. The survey of intensivists was conducted in 9 hospitals in Saint Petersburg and the Leningrad Region from July 2023 to July 2024. Statistical information processing was carried out using the Jamovi software package.
Results. The study included 381 questionnaires. Long ICU stay ( > 14 days) (AOR: 0.373; 95% CI: 0.183–0.758, p = 0.006; 0.492; 0.246–0.985, p = 0.045), emergency surgeries and procedural complications (1.283; 1.071–1.537, p = 0.007; 1.387; 1.136–1.694, p = 0.001), as well as lack of data on oxygen therapy and respiratory support in the transfer epicrisis (0.315; 0.172–0.576, p < 0.001; 0.505; 0.278–0.919, p = 0.025) increase the chances of 24- and 48-hour unplanned ICU readmission. Transfer of patients from the ICU to «off-hours» (1.244; 1.020–1.517, p = 0.031; 1.518; 1.243–1.853, p < 0.001) was a risk factor for the 48- and 72-hour periods. Registration of adverse acute cardiovascular events (2.876; 1.368–6.047, p = 0.005; 2.578; 1.390–4.780, p = 0.003) increased unplanned ICU readmission in the 48-hour and 7-day periods. Sepsis in a patient in the ICU was considered by respondents to be an independent predictor of ICU readmissions for all periods except the 24-hour period. Characteristic predictors of unplanned ICU readmissions also were: for 24-hour – the impossibility of conducting «round-the-clock» laboratory and instrumental diagnostics (0.764; 0.639–0.914, p = 0.003), patient readmission due to the need to free up a ICU bed (1.345; 1.138–1.589, p = 0.001), failure to hold council (0.507; 0.270–0.954, p = 0.035); for 72-hour – physician experience (0.968; 0.939–0.997, p = 0.033); for 14 days – Mechanical Ventilation > 7 days (1.674; 1.025–2.734, p = 0.040).
Conclusion. The analysis of the opinions of intensivists made it possible to identify independent and determine modifiable predictors of early and late unplanned readmission of the patient to the ICU.
About the Authors
I. A. RuslyakovaRussian Federation
Ruslyakova Irina A., Cand. of Sci. (Med.), Assistant of the V. L. Vanevskii Department of Anesthesiology and Intensive Care, Head of the Department of Anesthesiology and Intensive Care for medical patients
47, Piskarevsky pr., Saint Petersburg, 195067
V. S. Afonchikov
Russian Federation
Afonchikov Vyacheslav S., Cand. of Sci. (Med.), Intensivist, Head of the Department of Anesthesiology and Intensive Care
3, letter A, Budapeshtskaya str., Saint Petersburg, 192242
E. A. Morozov
Russian Federation
Morozov Evgeny A., Cardiologist, Intensivist, Deputy Chief Physician for Anesthesiology and Intensive Care
85, Bolshoy V.O. pr., Saint Petersburg, 199106
V. V. Gomonova
Russian Federation
Gomonova Veronika V., Deputy Chief Physician for Therapy
47, Piskarevsky pr., Saint Petersburg, 195067
A. S. Zhernokleev
Russian Federation
Zhernokleev Andrey S., Intensivist, Head of the Intensive Care Department
3, Gazovy Zavod str., Saint Petersburg, 197762
K. M. Magomedisaev
Russian Federation
Magomedisaev Kurban M., Intensivist
56, Liteyny pr., Saint Petersburg, 191014
S. A. Nechayev
Russian Federation
Nechayev Sergey A., Intensivist
4, Solidarnosti str., Saint Petersburg, 193312
E. Z. Shamsutdinova
Russian Federation
Shamsutdinova Elvina Z., Anesthesiologist of the Department of Intensive Care for medical patients
47, Piskarevsky pr., Saint Petersburg, 195067
M. V. Bezrodny
Russian Federation
Bezrodny Maksim V., Intensivist of the Intensive Care Dep
15A, build. 1, Roshchinskaya str., Gatchina, Leningrad Region, 188300
A. E. Tanchuk
Russian Federation
Tanchuk Alexandra E., Clinical Resident of the V. L. Vanevskii Department of Anesthesiology and Intensive Care
47, Piskarevsky pr., Saint Petersburg, 195067
K. I. Shirokov
Russian Federation
Shirokov Kirill I., Student
47, Piskarevsky pr., Saint Petersburg, 195067
D. A. Chernyshev
Russian Federation
Chernyshev Denis A., Cand. of Sci. (Med.), Deputy Chief Physician for Surgery
14, A, Vavilovih str., Saint Petersburg, 195257
M. Yu. Kabanov
Russian Federation
Kabanov Maksim Yu., DR. of Sci. (Med.), Professor, Head; Chief Freelance Geriatrician of the Saint Petersburg Healthcare Committee, Honored Doctor of the Russian Federation
eLibrary AuthorID: 333633
14, letter A, Vavilovykh str., Saint Petersburg, 195257
References
1. Gudanis O. A., Lebedinskii K. M. Intensive care unit readmission. Anesteziologiya I Reanimatologiya, 2018, vol. 4, pp. 15–21. (In Russ.). https://doi.org/10.17116/anaesthesiology201804115.
2. Al-Jaghbeer M. J., Tekwani S. S., Gunn S. R. et al. Incidence and Etiology of Potentially Preventable ICU Readmissions. Crit Care Med, 2016, vol. 44, no. 9, pp. 1704–1709. https://doi.org/10.1097/CCM.0000000000001746.
3. Ashton C. M., Del Junco D. J., Souchek J. et al. The association between the quality of inpatient care and early readmission: a meta-analysis of the evidence. Med Care, 1997, vol. 35, no. 10, pp. 1044–1059. https://doi.org/10.1097/00005650-199710000-00006.
4. Chan K. S., Tan C. K., Fang C. S. et al. Readmission to the intensive care unit: An indicator that reflects the potential risks of morbidity and mortality of surgical patients in the intensive care unit. Surg Today, 2009, vol. 39, no. 4, pp. 295–299. https://doi.org/10.1007/s00595-008-3876-6.
5. Fink A. How to Conduct Surveys Edition 6th. Los Angeles, USA: UCLA, 2016, P. 224. ISBN: 1506347134.
6. Grochla M., Saucha W., Borkowski J. et al. Readmission to the intensive care unit – epidemiology, prediction and clinical consequences. Wiad Lek, 2019, vol. 72, no. 7, pp. 1387–1396.
7. Hervé M. E. W., Zucatti P. B., Lima M. A. D. D. S. Transition of care at discharge from the Intensive Care Unit: a scoping review. Rev Lat Am Enfermagem, 2020, vol. 28, P. e3325. https://doi.org/10.1590/1518-8345.4008.3325.
8. Ho K. M., Dobb G. J., Lee K. Y. et al. The effect of comorbidities on risk of intensive care readmission during the same hospitalization: a linked data cohort study. J Crit Care, 2009, vol. 24, no. 1, pp. 101–117. https://doi.org/10.1016/j.jcrc.2007.11.015.
9. Lehmann F., Potthoff A. L., Borger V. et al. Unplanned intensive care unit readmission after surgical treatment in patients with newly diagnosed glioblastoma – forfeiture of surgically achieved advantages? Neurosurg Rev, 2023, vol. 46, no. 1, P. 30. https://doi.org/10.1007/s10143-022-01938-6.
10. Mady A. F., Al-Odat M. A., Alshaya R. et al. Mortality Rates in Early versus Late Intensive Care Unit Readmission. Saudi J Med Med Sci, 2023, vol. 11, no. 2, pp. 143–149. https://doi.org/10.4103/sjmms.sjmms_634_22.
11. Nates J. L., Nunnally M., Kleinpell R. et al. ICU Admission, Discharge, and Triage Guidelines: A Framework to Enhance Clinical Operations, Development of Institutional Policies, and Further Research. Crit Care Med, 2016, vol. 44, no. 8, pp. 1553–1602. https://doi.org/10.1097/CCM.0000000000001856.
12. Plotnikoff K. M., Krewulak K. D., Hernández L. et al. Patient discharge from intensive care: an updated scoping review to identify tools and practices to inform high-quality care. Crit Care, 2021, vol. 25, no. 1, P. 438. https://doi.org/10.1186/s13054-021-03857-2.
13. Sharp E. A., Hall M., Berry J. G. et al. Frequency, Characteristics, and Outcomes of Patients Requiring Early PICU Readmission. Hospital pediatrics, 2023, vol. 13, no. 8, pp. 678–688. https://doi.org/10.1542/hpeds.2022-007100.
14. Vlayen A., Verelst S., Bekkering G. E. et al. Incidence and preventability of adverse events requiring intensive care admission: a systematic review. J Eval Clin Pract, 2012, vol. 18, no. 2, pp. 485–497. https://doi.org/10.1111/j.1365-2753.2010.01612.
15. Vollam S., Dutton S., Lamb S. et al. Out-of-hours discharge from intensive care, in-hospital mortality and intensive care readmission rates: a systematic review and meta-analysis. Intensive Care Med, 2018, vol. 44, no. 7, pp.1115–1129. https://doi.org/10.1007/s00134-018-5245-2.
16. Wagner J., Gabler N. B., Ratcliffe S. J. et al. Outcomes among patients discharged from busy intensive care units. Ann Intern Med, 2013, vol. 159, no. 7, pp. 447–455. https://doi.org/10.7326/0003-4819-159-7-201310010-00004.
17. Yin Y. L., Sun M. R., Zhang K. et al. Status and Risk Factors in Patients Requiring Unplanned Intensive Care Unit Readmission Within 48 Hours: A Retrospective Propensity-Matched Study in China. Risk Manag Healthc Policy, 2023, vol. 16, pp. 383–391. https://doi.org/10.2147/RMHP.S399829.
Review
For citations:
Ruslyakova I.A., Afonchikov V.S., Morozov E.A., Gomonova V.V., Zhernokleev A.S., Magomedisaev K.M., Nechayev S.A., Shamsutdinova E.Z., Bezrodny M.V., Tanchuk A.E., Shirokov K.I., Chernyshev D.A., Kabanov M.Yu. Risk factors for early and late unplanned readmissions to the intensive care unit – results of a survey among intensivist. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2025;22(1):68-79. (In Russ.) https://doi.org/10.24884/2078-5658-2025-22-1-68-79