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COMPARISON OF LOCAL AND SYSTEM INTRODUCTION OF TRANEXAMIC ACID IN ENDOPROSTHESIS REPLACEMENT OF THE KNEE JOINT

https://doi.org/10.21292/2078-5658-2016-13-2-44-49

Abstract

The randomized controlled trial was conducted to compare intravenous and intra-articular injection of tranexamic acid (dose of 15 mg/kg) in the combination with three hour closure of the drainage in case of total endoprosthesis replacement of knee joint. The local use of the medication proved to have the significant blood saving effect.

 

About the Authors

A. A. Tyuryapin
N. A. Semashko Northern Medical Clinical Center of Federal Medical Biological Agency, Arkhangelsk
Russian Federation


D. B. Borisov
N. A. Semashko Northern Medical Clinical Center of Federal Medical Biological Agency, Arkhangelsk
Russian Federation


I. A. Fomkina
N. A. Semashko Northern Medical Clinical Center of Federal Medical Biological Agency, Arkhangelsk
Russian Federation


D. V. Kozlova
N. A. Semashko Northern Medical Clinical Center of Federal Medical Biological Agency, Arkhangelsk
Russian Federation


E. M. Maslova
N. A. Semashko Northern Medical Clinical Center of Federal Medical Biological Agency, Arkhangelsk
Russian Federation


M. Yu. Kirov
Northern State Medical University, Arkhangelsk
Russian Federation


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Review

For citations:


Tyuryapin A.A., Borisov D.B., Fomkina I.A., Kozlova D.V., Maslova E.M., Kirov M.Yu. COMPARISON OF LOCAL AND SYSTEM INTRODUCTION OF TRANEXAMIC ACID IN ENDOPROSTHESIS REPLACEMENT OF THE KNEE JOINT. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2016;13(2):44-49. (In Russ.) https://doi.org/10.21292/2078-5658-2016-13-2-44-49



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