Anesthesia, Sedation and Memory – Is Everything So Simple?
https://doi.org/10.21292/2078-5658-2022-19-4-80-88
Abstract
The study of neural plasticity and related memory functions is one of the fundamental fields in anesthesiology. Understanding this issue is very important both for the physician - the anesthesiologist-resuscitator, and for the patient. This review of the literature describes structures and processes of the central nervous system which in a sense are the target for the amnestic action of sedation and anesthesia medications. The possibilities of implicit and explicit memory formation depending on different levels of sedation and anesthesia are considered. Special attention is paid to the mechanism of action of GABAergic drugs on the processes of memory consolidation and reconsolidation.
About the Authors
V. O. Churakov
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Vyacheslav O. Churakov, Post Graduate Student of Anesthesiology and Intensive Care Department of Clinical Medicine Institute
8, Bd. 2, Trubetskaya St., Moscow, 119991
A. Yu. Zaitsev
Sechenov First Moscow State Medical University (Sechenov University); Russian Surgery Research Center Named After B. V. Petrovsky
Russian Federation
Russian Federation
Andrey Yu. Zaitsev, Doctor of Medical Sciences, Associate Professor of Anesthesiology and Intensive Care Department of Clinical Medicine Institute
8, Bd. 2, Trubetskaya St., Moscow, 119991
K. V. Anokhin
Lomonosov Moscow State University
Russian Federation
Russian Federation
Konstantin V. Anokhin, Doctor of Medical Sciences, Professor, Academician of RAS, Director of the Institute for Advanced Brain Research
1, Leninskie Gory, Moscow, 119991
K. V. Dubrovin
Sechenov First Moscow State Medical University (Sechenov University); Russian Surgery Research Center Named After B. V. Petrovsky
Russian Federation
Russian Federation
Kirill V. Dubrovin, Candidate of Medical Sciences, Assistant of Anesthesiology and Intensive Care Department of Clinical Medicine Institute
8, Bd. 2, Trubetskaya St., Moscow, 119991
A. M. Bukinich
Lomonosov Moscow State University
Russian Federation
Russian Federation
Aleksey M. Bukinich, Student of Psychology Faculty
1, Leninskie Gory, Moscow, 119991
G. D. Vzorin
Lomonosov Moscow State University
Russian Federation
Russian Federation
Gleb D. Vzorin, Student of Psychology Faculty
1, Leninskie Gory, Moscow, 119991
V. V. Nurkova
Lomonosov Moscow State University
Russian Federation
Russian Federation
Veronika V. Nurkova, Doctor of Psychological Sciences, Professor of General Psychology Department
1, Leninskie Gory, Moscow, 119991
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Review
For citations:
Churakov V.O., Zaitsev A.Yu., Anokhin K.V., Dubrovin K.V., Bukinich A.M., Vzorin G.D., Nurkova V.V. Anesthesia, Sedation and Memory – Is Everything So Simple? Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2022;19(4):80-88. (In Russ.) https://doi.org/10.21292/2078-5658-2022-19-4-80-88
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