PHARMACOECONOMIC ANALYSIS OF THE IMPACT ON THE BUDGET COSTS OF ADDING DEXMEDETOMIDINE (DEXDOR) INTO THE LIST OF VITAL AND ESSENTIAL DRUGS
https://doi.org/10.21292/2078-5658-2015-12-6-32-39
Abstract
Analysis of four pharmacoeconomic replacement models for midazolam, propofol and phentanyl with dexmedetomidine for sedation in resuscitation and intensive care unit (RICU) shows increase of the annual costs (at current prices) by 14-28 million rubles (at prices of the reference country – by 9-23 million rubles). The calculation of the RICU stay cost in the rates of the health care providers rather than in that of the Compulsory Health Insurance (CHI) effects a saving of up to 1 billion rubles at current prices and up to 3.5 billion rubles at prices of the reference country.
About the Authors
S. L. Plavinskiy
I. I. Mechnikov Northern-Western Medical University, St. Petersburg
Russian Federation
Russian Federation
P. I. Shabalkin
D. Rogachev Federal Research Clinical Center of Children Hematology, Oncology
and Immunology, Moscow
Russian Federation
Russian Federation
A. E. Karelov
I. I. Mechnikov Northern-Western Medical University, St. Petersburg
Russian Federation
Russian Federation
References
1. Belyshev S.А., Levit А.L., Leyderman I.N. et al. Do we control the sedation in RICU? Results of multicenter trial. Anesteziol. i Reanimatol., 2012, no. 2, pp. 72-77. (In Russ.)
2. AWMSG Secretariat. Assessment report – advice no. 2312. dexmedetomidine 100 micrograms/ml concentrate for solution for infusion: Tech. rep. AWMSG Secretariat: AWMSG, 2012.
3. Dasta J.F., Kane-Gill S.L., Pencina M. et al. A cost-minimization analysis of dexmedetomidine compared with midazolam for long-term sedation in the intensive care unit. Crit. Care Med., 2010, vol. 38, no. 2, pp. 497-503.
4. Jakob S.M., Ruokonen E., Grounds R.M. et al. Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA, 2012, vol. 307, no. 11, pp. 1151-1160.
5. Lachaine J., Beauchemin C. et al. Economic evaluation of dexmedetomidine relative to midazolam for sedation in the intensive care unit. Can.J.Hosp. Pharm., 2012, vol. 65, no. 2, pp. 103-110.
6. Riker R.R., Shehabi Y., Bokesch P.M. et al. Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. JAMA, 2009, vol. 301, no. 5, pp. 489-499.
7. Tan J.A., Ho K.M. et al. Use of dexmedetomidine as a sedative and analgesic agent in critically ill adult patients: a meta-analysis. Int. Care Med., 2010, vol. 36, no. 6, pp. 926-939.
8. Turunen H., Jakob S.M., Ruokonen E. Dexmedetomidine versus standard care sedation with propofol or midazolam in intensive care – an economic evaluation. Crit. Care, 2015, vol. 19, pp. 67.
9. Orion, data on file. http://orion-file-recovery-software.en.softonic.com/ download
10. Wild C, Narath M. et al. Evaluating and planning ICUs: methods and approaches to differentiate between need and demand. Health Policy. 2005, vol. 71, pp. 289-301.
11. URL http://szgmu.ru/price/index.php?categoryID = 3981
12. URL:http://stats.oecd.org/Index.aspx?datasetcode = SNA_TABLE4
13. Available at: http://gov.spb.ru/law?d&nd=891836929&prevDoc=822401701.
14. Available at: http://www.semashko.com/node/442.
15. Available at: http://www.rlsnet.ru/prmoni_nom_id_13779_actmode_0.htm.
16. Available at: http://www.gov.karelia.ru/Karelia/2068/t/2068_8.html
17. Available at: http://www.gks.ru/bgd/regl/b11_34/IssWWW.exe/Stg/d01/ 02-02.htm
18. URL http://szgmu.ru/price/index.php?categoryID = 3981
19. URL:http://www.ckb-rzd.ru/php/content.php?id = 844
20. Available at: http://www.ckbran.ru/price/hospital/?id = 707
Review
For citations:
Plavinskiy S.L., Shabalkin P.I., Karelov A.E. PHARMACOECONOMIC ANALYSIS OF THE IMPACT ON THE BUDGET COSTS OF ADDING DEXMEDETOMIDINE (DEXDOR) INTO THE LIST OF VITAL AND ESSENTIAL DRUGS. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2015;12(6):32-39. (In Russ.) https://doi.org/10.21292/2078-5658-2015-12-6-32-39
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