APPLICATION OF DISTANT PRE-CONDITIONING TECHNIQUE IN PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY
https://doi.org/10.21292/2078-5658-2015-12-4-26-31
Abstract
The abstract describes the prospective randomized study which included 60 patients with severe traumatic brain injuries divided into two groups. In the group under the study (n = 30) the distant ischemic preconditioning has been applied which is commonly used for planned surgeries and it allowed achieving statically significant decrease in the time of coming out from coma, the duration of stay in the intensive care ward and increase the rate of 28 day survival.
About the Authors
L. L. PlotkinRussian Federation
Yu. P. Klink
Russian Federation
References
1. Babayan E., Zel'man V.L., Polushin Yu.S et al. Brain protection from ischemia: state of the problem. Anesteziol. i Reanimatol., 2005, no. 4, pp. 4-14. (In Russ.)
2. Likhvantsev V.V., Moroz V.V., Grebennikov O.А. et al. Ischemic and pharmacological preconditioning. Obsch. Reanimatol., 2012, vol. 8, no. 1, pp. 40-48. (In Russ.)
3. Sergienko V.I., Bondareva I.B. Matematicheskaya statistika v klinicheskikh issledovaniyakh. [Mathematical statistics for clinical trials]. Moscow, GEOTRAR Meditsina Publ., 2000, 256 p.
4. Tsarenko S.V. Neyroreanimatologiya. Intensivnaya terapiya cherepno-mozgovoy travmy. [Neurological critical care. Intensive care for traumatic brain injury]. Moscow, OAO Izdatelstvo Meditsina Publ., 2005, 352 p.
5. Tseytlin А.M., Lubnin А.Yu., Zel'man V.L Ischemic tolerance (pre-conditioning) of the brain. Anesteziol. i Reanimatol., 2008, no. 2, pp. 41-46. (In Russ.)
6. Brattor S., Bullok M.R., Raudall M.C.et al. Guidelines for the management of severe traumatic brain injure. J. Neurotrauma, 2007, vol. 24, no. 1, pp. 1-106.
7. Charlson M.E., Pompei P., Ales K.L. et al. A new method of classifying prognostic co-morbidity in longitudinal studies: development and validation. J. Chron. Dis., 1987, vol. 40, pp. 373-383.
8. Knaus W.A., Sun V., Nyston P.O. et al. Evaluation of definition for sepsis. Chest, 1992, vol. 101, pp. 1656-1662.
9. Lu J., Mormaron A., Choi S. et al. Mortality from traumatic brain injure. Acta Neurochir., 2007, vol. 95, pp. 281-285.
10. Marshal J.C., Cook D.J, Criston N.V. et al. Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit. Care Med., 1995, vol. 23, pp. 1638-1652.
11. Murry C.E., Jennings R.B., Reimer K.A. Preconditioniny with ischemia: a delay of lethal celf injure in ischemia myocardium. Circulation, 1986, vol. 74, no. 5, pp. 1124-1136.
12. Tapuria N., Kumor Y., Habib M.M. et al. Remote ischemia preconditioning: a novel protective method from ischemia reperfusion injure. J. Surg Res., 2008, vol. 150, no. 2, pp. 304-330.
Review
For citations:
Plotkin L.L., Klink Yu.P. APPLICATION OF DISTANT PRE-CONDITIONING TECHNIQUE IN PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2015;12(4):26-31. (In Russ.) https://doi.org/10.21292/2078-5658-2015-12-4-26-31