Reduction of sevoflurane and fentanyl consumption through dexmedetomidine use as a part of general anesthesia in oncogynecological surgery (a prospective blind randomized study)
https://doi.org/10.21292/2078-5658-2019-16-5-49-55
Abstract
The objective: to compare hemodynamic parameters, expiratory concentration of sevoflurane, fentanyl consumption during the surgery, the intensity of the pain syndrome during general combined anesthesia with and without dexmedetomidine.
Subjects and methods: a prospective, blind, randomized study was performed in patients with oncogynecological disorders divided into two groups, where dexmedetomidine was used and not.
Results. In the studied groups, changes in hemodynamics, expiratory concentration of sevoflurane, and fentanyl consumption were observed. There was no difference in the pain intensity between the groups.
Conclusions. The expiratory concentration of sevoflurane, as well as the consumption of fentanyl, were lower in the group where dexmedetomidine was used. The intensity of the pain syndrome did not differ between two groups.
About the Authors
K. A. Tsygаnkov
S.M. Kirov Military Medical Academy
Russian Federation
Russian Federation
Kirill A. Tsygankov - Candidate of Medical Sciences, Teacher of Military Anesthesiology and Intensive Care Department.
6, Academician Lebedev St., St. Petersburg, 194044.
Phone: +7 (812) 329-71-21.
R. E. Lаkhin
S.M. Kirov Military Medical Academy
Russian Federation
Russian Federation
Roman E. Lakhin - Doctor of Medical Sciences, Professor of Military Anesthesiology and Intensive Care Department.
6, Academician Lebedev St., St. Petersburg, 194044.
Phone: +7 (812) 329-71-21.
D. A. Аveryanov
S.M. Kirov Military Medical Academy
Russian Federation
Russian Federation
Dmitry A. Аveryanov - Candidate of Medical Sciences, Teacher of Military Anesthesiology and Intensive Care Department.
6, Academician Lebedev St., St. Petersburg, 194044.
Phone: +7 (812) 329-71-21.
A. V. Schegolev
S.M. Kirov Military Medical Academy
Russian Federation
Russian Federation
Aleksey V. Schegolev - Doctor of Medical Sciences, Head of Military Anesthesiology and Intensive Care Department (Head of the Clinic).
6, Academician Lebedev St., St. Petersburg, 194044.
Phone: +7 (812) 329-71-21.
A. A. Аndreenko
S.M. Kirov Military Medical Academy
Russian Federation
Russian Federation
Aleksandr A. Аndreenko - Candidate of Medical Sciences, Deputy Head of Military Anesthesiology and Intensive Care Department (Deputy Head of Clinic).
6, Academician Lebedev St., St. Petersburg, 194044.
Phone: +7 (812) 329-71-21.
A. D. Khаlikov
City Clinical Oncology Dispensary
Russian Federation
Russian Federation
Azam D. Khalikov - Candidate of Medical Sciences, Head of Anesthesiology and Intensive Care Department.
56, Veteranov Ave.,St. Petersburg, 198255.
Phone: +7 (812) 607-06-81.
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Review
For citations:
Tsygаnkov K.A., Lаkhin R.E., Аveryanov D.A., Schegolev A.V., Аndreenko A.A., Khаlikov A.D. Reduction of sevoflurane and fentanyl consumption through dexmedetomidine use as a part of general anesthesia in oncogynecological surgery (a prospective blind randomized study). Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2019;16(5):49-55. (In Russ.) https://doi.org/10.21292/2078-5658-2019-16-5-49-55
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