SEDATION IN DENTISTRY AND OUT-PATIENT MAXILLOFACIAL SURGERY. THEORY AND PRACTICE
https://doi.org/10.21292/2078-5658-2018-15-3-62-73
Abstract
The article describes sedation in dentistry and out-patient maxillofacial surgery. The definitions of sedation, psychoemotional comfort and discomfort are thoroughly described and introduced. A special emphasis is put on pathophysiology of psychoemotional discomfort and peri-operative stress. According to modern data, the objectives to be achieved by an anesthesiologist have been reviewed: provision of psychoemotional inhibition (as a basis of comfort staying in a dental chair), but not depression of consciousness as it used to be before.
With much detail it analyzes complication occurring during anesthesia; their correlations with age, concurrent conditions, anesthetic agent and doctor's professional level are highlighted.
The article presents a clinical picture of sedation depending on the depression of consciousness, respiration, and hemodynamics (ADA and ASA, 2016). It depicts thoroughly the state of minimal sedation (anxiolysis), moderate sedation (awake sedation), deep sedation and general anesthesia. Special attention is paid to the provision of patient's safety related to supporting airway patency and hemodynamics.
The article presents methods of sedation from the position of modern global data and personal experience of authors. Methods of medication administration are mentioned: enteral, parenteral, including intra-nasal which is fairly popular of late.
Special attention is paid to specific problems of sedation, presence of motion activity, psychoemotional agitation, compulsive coughing. Potential causes of these events are described, in particular, correlation between psychoemotional agitation with dysregulation of GABA-ergic and dopaminergic systems.
Current data on the intra-operative monitoring are presented, as an important component of the patient's safety during sedation. Additionally to Harvard Standard, it is recommended to use capnography and monitoring of sedation depth through bispectral index.
About the Authors
A. Yu. ZаytsevRussian Federation
Andrey Yu. Zaitsev - Candidate of Medical Sciences, Leading Researcher of Anesthesiology and Intensive Care Department.
2, Abrikosovsky Lane, Moscow, 119991
V. A. Svetlov
Russian Federation
Vsevolod A. Svetlov - Doctor of Medical Sciences, Professor, Senior Researcher of Anesthesiology and Intensive Care Department.
2, Abrikosovsky Lane, Moscow, 119991
K. V. Dubrovin
Russian Federation
Kirill V. Dubrovin - Anesthesiologist and Emergency Physician of Anesthesiology and Intensive Care Department.
2, Abrikosovsky Lane, Moscow, 119991
References
1. Bobrinskaya I.G., Sigaev V.V. Main stages of pain relief in dentistry. History of dentistry. Vserossiyskaya konferentsiya (s mezhdunarodnym uchastiem). Doklady i tezisy. [All-Russian Conference (with international conference). Reports and abstracts]. Moscow, 2007. (In Russ.)
2. Bobrov А.P., Revyuk Yu.V. Actual issues of pain relief in the practice of a dentist. Ab origine till present. Vserossiyskaya konferentsiya (s mezhdunarodnym uchastiem). Doklady i tezisy. [All-Russian Conference (with international conference). Reports and abstracts]. Moscow, 2007. (In Russ.)
3. Bogdanova I.V. Role of dopamine in the mechanisms of formation of some disorders of central nervous system and addictions (literature review). Ukrainskiy Visnik Psikhonevrologii, vol. 19, no. 67, 2011, pp. 5-8.
4. Buzunov R.V., Tsareva E.V. Sindrom bespokoynykh nog: Uchebnoe posobie dlya vrachey. [Restless legs syndrome. Doctor's handbook]. Moscow, 2011. 27 p.
5. Bunyatyan А.А. Rukovodstvo po anesteziologii. [Anesthesiology Guidelines]. Moscow, Meditsina Publ., 1994, pp. 168-185.
6. Bunyatyan А.А., Mescheryakov А.V., Tsibulyak V.N. Аtaralgeziya. [Ataralgesia]. 1983, pp. 170.
7. Bunyatyan А.А., Mizikov V.M. Anasteziologiya. Natsionalnoye rukovodstvo. [Anesthesiology. National Guidelines]. Moscow, GEOTAR-Media Publ., 2011, pp. 506-507.
8. Burgonskiy V.G. Modern technologies of local pain relief in dentistry. Sovremennaya Stomatologiya, 2009, vol. 2, pp. 99-104. (In Russ.)
9. Dubynin V.A. Regulyatornye sistemy organizma cheloveka. Glava 3. Obschaya fiziologiya nervnoy sistemy. [Human regulatory systems. Chapter 3. In: General physiology of nervous system]. Moscow, Drofa Publ., 2003, pp. 144-153.
10. Zhorov I.S. Obschee obezbolivanie v khirurgii. Glava 3. Bioehlektricheskaya aktivnost mozga pri razlichnykh narkozakh. [General pain relief in surgery. Chapter 3. In: Brian electrobiological activity under various anesthesia]. Gosudarstvennoye Izdatelstvo Meditsinskoy Literatury Publ., Moscow, Medgiz Publ., 1959. pp. 78-88.
11. Zaytsev A.Yu. Korrektsiya psikhoemotsionalnogo statusa u khirurgicheskikh bolnykh v usloviyakh regionarnoy anestezii. Diss. kand. med. nauk. [Management of psychoemotional state in the patients undergoing surgery with regional anesthesia. Cand. Diss.]. Moscow, 2003, 135 p.
12. Illarionova E.А., Syrovatskiy I.P. Khimiko-toksikologicheskiy analiz proizvodnykh amfetamina: Uch. posobie. [Chemical and toxicological analysis of amphetamine derivatives. Handbook]. Irkutsk, IGMU Publ., 2016.
13. Katunina E.А., Аvakyan G.N., Titova N.V. et al. Levodopa - from development to new products. Journal Nevrologii i Psikhiatrii, 2010, no. 4, pp. 97-103. (In Russ.)
14. Samokhvalov V.P. Psikhiatriya. Uchebnoe posobie dlya studentov meditsinskikh vuzov». Glava 8. Chastnaya psikhiatriya. Аffektivnye rasstroystva nastroeniya (F3). [Private psychiatry. Affective disorders (F3). Chapter 8. In: Psychiatry. Handbook for students of medical universities]. pp. 175-178.
15. Svetlov V.А., Zaytsev А.Yu., Kozlov S.P. Psychoemotional comfort – is it a special component of anesthesia? Anesteziologiya i Reanimatologiya, 2008, no. 5, pp. 88-91. (In Russ.)
16. Svetlov V.А., Zaytsev А.Yu., Kozlov S.P. Balanced anesthesia based on regional blocks: strategy and tactics. Anesteziologiya i Reanimatologiya, 2006, no. 4, pp. 4-12. (In Russ.)
17. Solovieva I.K. Anxiety medications: yesterday, today, tomorrow. Russky Meditsinsky Journal, 2006, vol. 14, no. 5, pp. 385-389. (In Russ.)
18. Tseytlin А.M., Lubnin А.Yu. Motor agitation in diprivan anesthesia: is it dangerous? Vestn. Intensiv. Ter., 1999, vol. 1, pp. 23-27. (In Russ.)
19. Agostoni M., Fanti L., Gemma M. et al. Adverse events during monitored anesthesia care for GI endoscopy: an 8-year experience. Gastrointestinal Endoscopy, 2011, vol. 74, no. 2, pp. 266-275.
20. Ahmed S.S., Hicks S., Slaven J.E. et al. Intermittent bolus versus continuous infusion of propofol for deep sedation during ABR/nuclear medicine studies. J. Pediatric Intens. Care, 2017, vol. 6, no. 3, pp. 176-181.
21. American Dental Association. Guidelines for the use of sedation and general anesthesia by dentists, 2012. Available at: https://www.ada.org/~/media/ADA/About%20the%20ADA/Files/anesthesia_use_guidelines.ashx. Accessed May 10, 2016.
22. American Dental Association. Guidelines for the use of sedation and general anesthesia by dentists. Adopted by the ADA House of Delegates, October. 2016.
23. Anderson K.J., Kenny G.N.C. Intravenous drugs for sedation: target-controlled, patient-controlled and patient-maintained delivery. Total Intraven. Anesthesia Target Controlled Infusions. Springer, 2017, pp. 369-390.
24. Annequin D., Carbajal R., Chauvin P. et al. Fixed 50% nitrous oxide oxygen mixture for painful procedures: a French survey. Pediatrics, 2000, vol. 105, no. 4, pp. e47–e47.
25. Anthonappa R.P., Ashley P.F., Bonetti D.L. et al. Non-pharmacological interventions for managing dental anxiety in children. The Cochrane Library. 2017, URL: http://www.cochrane.org/CD012676/ORAL_non-pharmacological-interventions-managing-dental-anxiety-children.
26. Arpaci A.H., Isik B. Pediatric tooth extractions under sedoanalgesia. Pakistan J. Med. Sci., 2016, vol. 32, no. 5, pp. 1291.
27. Bennett J.D., Kramer K.J., Bosack R.C. How safe is deep sedation or general anesthesia while providing dental care? J. Am. Dental Association, 2015, vol. 146, no. 9, pp. 705-708.
28. Bailey P., Pace N. L., Ashburn M.A. et al. Frequent hypoxemia and apnea after sedation with midazolam and fentanyl. Anesthesiology, 1990, vol. 73, no. 5, pp. 826-830.
29. Bradt J., Dileo C., Shim M. Music interventions for preoperative anxiety. The Cochrane Library. 2013, URL: https://www.temple.edu/boyer/community/documents/musicintervntionsforpreoperativeanxiety.published.pdf
30. Chanavaz M., Ferri J., Donazzan M. Intravenous sedation in implantology. Revue de Stomatologie et de Chirurgie Maxilla-Faciale, 1997, vol. 98, no. 1, pp. 57-61.
31. Conway A., Rolley J., Sutherland J.R. Midazolam for sedation before procedures. The Cochrane Library. 2016, URL: http://www.cochrane.org/CD009491/ANAESTH_midazolam-sedation-procedures.
32. Coté G.A., Hovis R.M., Ansstas M.A. et al. Incidence of sedation-related complications with propofol use during advanced endoscopic procedures. Clin. Gastroenterol. Hepatology, 2010, vol. 8, no. 2, pp. 137-142.
33. Devasya A., Sarpangala M. Dexmedetomidine: a review of a newer sedative in dentistry. J. Clin. Ped. Dentistry, 2015, vol. 39, no. 5, pp. 401-409.
34. Egan T.D., Lemmens H.J.M., Fiset P. et al. The pharmacokinetics of the new short-acting opioid remifentanil (GI87084B) in healthy adult male volunteers. Anesthesiology, 1993, vol. 79, no. 5, pp. 881-892.
35. Esen E., Ustün Y., Balcioğlu O. et al. Evaluation of patient-controlled remifentanil application in third molar surgery. J. Oral Maxillofacial Surgery, 2005, vol. 63, no. 4, pp. 457-463.
36. Faddy S.C., Garlick S.R. A systematic review of the safety of analgesia with 50% nitrous oxide: can lay responders use analgesic gases in the prehospital setting?. Emergency Med. J. 2005, vol. 22, no. 12, pp. 901-908.
37. Fong C.C.Y., Kwan A. Patient-controlled sedation using remifentanil for third molar extraction. Anaest. Intens. Care, 2005, vol. 33, no. 1, pp. 73.
38. Ghajari M.F., Ansari G., Soleymani A.A. et al. Comparison of oral and intranasal midazolam/ketamine sedation in 3‒6-year-old uncooperative dental patients. J. Dental Research, Dental Clinics, Dental Prospects, 2015, vol. 9, no. 2, pp. 61.
39. Giovannitti Jr.J.A., Thoms S.M., Crawford J.J. Alpha-2 adrenergic receptor agonists: a review of current clinical applications. Anesthesia Progress, 2015, vol. 62, no. 1, pp. 31-38.
40. Halai T., Naqvi A., Steel C. et al. Complications of conscious sedation: causes and management. Dental Update, 2017, vol. 44, no. 11, pp. 1034-1040.
41. Hall D.L., Weaver J., Ganzberg S. et al. Bispectral EEG index monitoring of high-dose nitrous oxide and low-dose sevoflurane sedation. Anest. Progress, 2002, vol. 49, no. 2, pp. 56.
42. Hallonsten A.L., Koch G., Schröder U. Nitrous oxide‐oxygen sedation in dental care. Community dentistry and oral epidemiology, 1983, vol. 11, no. 6, pp. 347-355.
43. Hanamoto H., Sugimura M., Morimoto Y. et al. Cough reflex under intravenous sedation during dental implant surgery is more frequent during procedures in the maxillary anterior region. J. Oral Maxillofacial Surgery, 2013, vol. 71, no. 4, pp. e158–e163.
44. Hinkelbein J., Lamperti M., Akeson J. et al. European Society of Anaesthesiology and European Board of Anaesthesiology guidelines for procedural sedation and analgesia in adults. Europ. J. Anaesthesiology (EJA), 2018, vol. 35, no. 1, pp. 6-24.
45. http://apps.who.int/classifications/icd10/browse/2016/en#/F30.0
46. Inverso G., Dodson T. B., Gonzalez M.L. et al. Complications of intravenous sedation versus general anesthesia for adolescent patients receiving third-molar extraction. J. Oral Maxillofacial Surgery, 2015, vol. 73, no. 9, pp. e34.
47. Imagawa A., Fujiki S., Kawahara Y. et al. Satisfaction with bispectral index monitoring of propofol-mediated sedation during endoscopic submucosal dissection: a prospective, randomized study. Endoscopy, 2008, vol. 40, no. 11, pp. 905-909.
48. Jokelainen J., Udd M., Kylänpää L. et al. How patient-controlled sedation is adopted in clinical practice of sedation for endoscopic retrograde cholangiopancreatography? A prospective study of 1196 cases. Scandinav. J. Gastroenterology, 2017, vol. 52, no. 2, pp. 166-172.
49. Khan A.B., Kingsley T., Caroline P. Sublingual Tablets and the Benefits of the Sublingual Route of Administration. J. Pharmaceutical Research, 2017, vol. 16, no. 3, pp. 257-267.
50. Kim S.O., Kim Y.J., Hyun H.K. et al. Deep sedation with sevoflurane inhalation via a nasal hood for brief dental procedures in pediatric patients. Pediatr. Emergency Care, 2013, vol. 29, no. 8, pp. 926-928.
51. Kohjitani A., Egusa M., Shimada M. et al. Accumulated oropharyngeal water increases coughing during dental treatment with intravenous sedation. J. Oral Rehabilitation, 2008, vol. 35, no. 3, pp. 203-208.
52. Lane R.D., Schunk J.E. Atomized intranasal midazolam use for minor procedures in the pediatric emergency department. Pediatr. Emergency Care, 2008, vol. 24, no. 5, pp. 300-303.
53. Lahoud G.Y.G., Averley P.A., Hanlon M.R. Sevoflurane inhalation conscious sedation for children having dental treatment. Anaesthesia, 2001, vol. 56, no. 5, pp. 476-480.
54. Lee H.H., Milgrom P., Starks H. et al. Trends in death associated with pediatric dental sedation and general anesthesia. Pediatr. Anesthesia, 2013, vol. 23, no. 8, pp. 741-746.
55. Litman R.S., Berkowitz R.J., Ward D.S. Levels of consciousness and ventilatory parameters in young children during sedation with oral midazolam and nitrous oxide. Archives Pediatrics & Adolescent Med., 1996, vol. 150, no. 7, pp. 671-675.
56. Litt M.D. A model of pain and anxiety associated with acute stressors: distress in dental procedures. Behaviour Research and Therapy, 1996, vol. 34, no. 5-6, pp. 459-476.
57. Luhmann J.D., Kennedy R.M., Porter F.L. et al. A randomized clinical trial of continuous-flow nitrous oxide and midazolam for sedation of young children during laceration repair. Ann. Emergency Med. 2001, vol. 37, no. 1, pp. 20-27.
58. Miller R.D., Pardo M. Basics of Anesthesia E-Book. Elsevier Health Sciences, 2011, pp. 3-11.
59. Messieha Z.S., Ananda R.C., Hoffman W.E. et al. Bispectral Index System (BIS) monitoring reduces time to discharge in children requiring intramuscular sedation and general anesthesia for outpatient dental rehabilitation. Pediatric Dentistry, 2004, vol. 26, no. 3, pp. 256-260.
60. Nkansah P.J., Haas D.A., Saso M.A. Mortality incidence in outpatient anesthesia for dentistry in Ontario. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics, 1997, vol. 83, no. 6, pp. 646-651.
61. O'Halloran M. The use of anaesthetic agents to provide anxiolysis and sedation in dentistry and oral surgery. Austral. Med. J., 2013, vol. 6, no. 12, pp. 713.
62. Ozkan G., Ince M.E., Eskin M.B. et al. Sedoanalgesia for cardioversion: comparison of alfentanil, remifentanil and fentanyl combined with propofol and midazolam: a prospective, randomized, double-blind study. Eur. Rev. Med. Pharmacol. Sci., 2016, vol. 20, no. 6, pp. 1140-1148.
63. Picard V., Dumont L., Pellegrini M. Quality of recovery in children: sevoflurane versus propofol. Acta Anaesthesiologica Scandinavica, 2000, vol. 44, no. 3, pp. 307-310.
64. Powers K.S., Nazarian E.B., Tapyrik S.A. et al. Bispectral index as a guide for titration of propofol during procedural sedation among children. Pediatrics, 2005, vol. 115, no. 6, pp. 1666-1674.
65. Reuter N.G. Death related to dental treatment: a systematic review. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017, vol. 123, no. 2, pp. 194-204.
66. Roberts J.F., Curzon M.E.J., Koch G. et al. behaviour management techniques in paediatric dentistry. Eur. Archives Paediatric Dentistry, 2010, vol. 11, no. 4, pp. 166-174.
67. Roelofse J.A., Shipton E.A., de la Harpe C.J. Intranasal sufentanil/midazolam versus ketamine/midazolam for analgesia/sedation in the pediatric population prior to undergoing multiple dental extractions under general anesthesia: a prospective, double-blind, randomized comparison. Anesthesia Progress, 2004, vol. 51, no. 4, pp. 114.
68. Sanborn P.A., Michna E., Zurakowski D. et al. Adverse cardiovascular and respiratory events during sedation of pediatric patients for imaging examinations. Radiology, 2005, vol. 237, no. 1, pp. 288-294.
69. Sezgin O., Yaraş S., Ates F. et al. Effectiveness of sedoanalgesia in percutaneous liver biopsy premedication. Euroasian J. Hepato-Gastroenterology, 2017, vol. 7, no. 2, pp. 146-149.
70. Silver S. Balanced anesthesia. J. Am. Dental Society of Anesthesiology, 1959, vol. 6, no. 7, pp. 11.
71. Singh N., Pandey R.K., Saksena A.K. et al. A comparative evaluation of oral midazolam with other sedatives as premedication in pediatric dentistry. J. Clin. Pediatric Dentistry, 2002, vol. 26, no. 2, pp. 161-164.
72. Symington L., Thakore S. A review of the use of propofol for procedural sedation in the emergency department. Emerg. Med. J., 2006, vol. 23, no. 2, pp. 89-93.
73. Tomlin P.J., Gjessing J. Balanced regional analgesia – an hypothesis. Canad. Anaesthetists’ Society J., 1978, vol. 25, no. 5, pp. 412-415.
74. Treggiari M.M., Romand J.A., Yanez N.D. et al. Randomized trial of light versus deep sedation on mental health after critical illness. Crit. Care Med., 2009, vol. 37, no. 9, pp. 2527-2534.
75. Tryba M. Choices in sedation: the balanced sedation technique. Eur. J. Anaesthesiology (EJA), 1996, vol. 13, pp. 8-12.
76. Torun A.C., Yilmaz M.Z., Ozkan N. Sedative-analgesic activity of remifentanil and effects of preoperative anxiety on perceived pain in outpatient mandibular third molar surgery. Intern. J. Oral Maxillofacial Surgery, 2017, vol. 46, no. 3, pp. 379-384.
77. Woolley S.M., Chadwick B., Pugsley L. The interpersonal work of dental conscious sedation: A qualitative analysis. Community Dentistry and Oral Epidemiology, 2017, vol. 45, no. 4, pp. 330-336.
Review
For citations:
Zаytsev A.Yu., Svetlov V.A., Dubrovin K.V. SEDATION IN DENTISTRY AND OUT-PATIENT MAXILLOFACIAL SURGERY. THEORY AND PRACTICE. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2018;15(3):62-73. (In Russ.) https://doi.org/10.21292/2078-5658-2018-15-3-62-73