EFFECT OF THE SEDATIVE COMPONENT OF PREMEDICATION, ACHIEVED BY USING HYDROXYZINE HYDROCHLORIDE ON PSYCHOVEGETATIVE AND HORMONAL STATUS IN THOSE SUFFERING FROM THYROID DISORDERS
https://doi.org/10.21292/2078-5658-2017-14-1-24-28
Abstract
Goal of the study: to investigate the effect of hydroxyzine hydrochloride on the premedication efficacy in those suffering from thyroid disorders. Materials and methods. Premedication with hydroxyzine hydrochloride was performed in 102 patients suffering from thyroid disorders. Psychoemotional state of the patients before and after premedication was assessed by Spielberg-Khanin anxiety test, Hospital Anxiety and Depression Score, Personality Inventory of Bekhterev Institute (PIBI). Patients’ hormonal status was evaluated by the levels of thyreotrophin, thyroxin, triiodothyronine, cortisol in blood serum. Parameters of system hemodynamics, bispectral index were recorded. Results. High efficiency of pre-operative conditioning of the patients manifested through favorable changes in psychovegetative and hormonal rates was observed in case of the initial anxious and sensitive types of the attitude towards the disease. Conclusions. Prior to premedication, the type of the attitude towards the disease is to be defined as per PIBI in those suffering from thyroid disorders. In case of initial anxious and sensitive types of the attitude towards the disease the premedication with hydroxyzine hydrochloride is highly effective and results in favorable emotional and vegetative changes.
About the Authors
K. A. Badikova
Rostov State Medical University, Rostov-on-Don
Russian Federation
Post Graduate Student of Anesthesiology and Intensive Care Department
Russian Federation
Post Graduate Student of Anesthesiology and Intensive Care Department
V. M. Zhenilo
Rostov State Medical University, Rostov-on-Don
Russian Federation
Doctor of Medical Sciences, Professor, Head of Anesthesiology and Intensive Care Department
Russian Federation
Doctor of Medical Sciences, Professor, Head of Anesthesiology and Intensive Care Department
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Review
For citations:
Badikova K.A., Zhenilo V.M. EFFECT OF THE SEDATIVE COMPONENT OF PREMEDICATION, ACHIEVED BY USING HYDROXYZINE HYDROCHLORIDE ON PSYCHOVEGETATIVE AND HORMONAL STATUS IN THOSE SUFFERING FROM THYROID DISORDERS. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2017;14(1):24-28. (In Russ.) https://doi.org/10.21292/2078-5658-2017-14-1-24-28
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