Композитные индексы воспаления, иммунитета, питания. Формулы расчета, интерпретация, клиническое значение (обзор литературы)

Введение. Новые агрегированные гемацитометрические индексы соотношения нейтрофилов, лимфоцитов, тромбоцитов, моноцитов, С реактивного белка, альбумина могут быть многообещающими маркерами объективного состояния и динамики критических состояний в кардиологии, онкологии, инфекционной патологии и интенсивной терапии.

Цель – сравнение методик расчета новых композитных гемоцитометрических индексов и обсуждение их применения и эффективности при интенсивной терапии.

Материалы и методы. Проведен поиск литературы с использованием баз данных PubMed, Medline, Google Scholar в период 2020–2024 гг. В поиск включены публикации, индексируемые в Scopus.

Результаты. Комбинированные показатели, характеризующие статус воспаления, иммунитета, питания при проведении интенсивной терапии оказываются более точными в сравнении с традиционными одиночными гематологическими и биохимическими параметрами. Диагностическая ценность данных показателей до сих пор вариабельна, а при интенсивной терапии мало изучена.

Заключение. Использование гемоцитометрических, комбинированных (композитных) индексов в различных областях клинической медицины – объективно новый шаг в интерпретации лабораторных показателей.

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