PREVENTION OF HEART FAILURE IN NON-CARDIAC SURGERY WITH THE LOWER EJECTION FRACTION OF LEFT VENTRICULAR: LEVOSIMENDAN OR ANESTHETIC CARDIOPROTECTION? (randomized multi-centered trial)
https://doi.org/10.21292/2078-5658-2016-13-3-74-79
Abstract
Basing on the existing data about the positive impact of inhalation induction and anesthetic support (IIAS) and levosimendan it is planned to study and compare within framework of the coming study the impact of IIAS and pre-operative preparation through administration of levosimendan on the rates of myocardial contractility during intra and early post-operative periods, the need in inotropic agents, and 30-day and 1 year mortality of the patients with lower ejection fraction of left ventricular during surgery on infrarenal part of aorta.
About the Authors
V. V. Likhvantsev
M. F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow;
V. A. Negovsky Institute of General Critical Care, Moscow
Russian Federation
Doctor of Medical Sciences, Professor, Head of Intensive Care Department
Russian Federation
Doctor of Medical Sciences, Professor, Head of Intensive Care Department
D. N. Marchenko
V. V. Veresaev Municipal Clinical Hospital, Moscow
Russian Federation
Doctor of Anesthesiology and Intensive Care Department
Russian Federation
Doctor of Anesthesiology and Intensive Care Department
O. A. Grebenchikov
M. F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow;
V. A. Negovsky Institute of General Critical Care, Moscow
Russian Federation
Candidate of Medical Sciences, Senior Researcher of Microbiological Department
Russian Federation
Candidate of Medical Sciences, Senior Researcher of Microbiological Department
Yu. V. Ubasev
Military Medical Organisation, Golytsino, Moscow Region
Russian Federation
Military Medical Organisation, Resident Physician of Anesthesiology and Intensive Care Department no. 2, Golytsino
Russian Federation
Military Medical Organisation, Resident Physician of Anesthesiology and Intensive Care Department no. 2, Golytsino
T. S. Zabelina
M. F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow
Russian Federation
Researcher of Intensive Care Department
Russian Federation
Researcher of Intensive Care Department
S. S. Timoshin
V. V. Veresaev Municipal Clinical Hospital, Moscow;
V. A. Negovsky Institute of General Critical Care, Moscow
Russian Federation
Candidate of Medical Sciences, Head of Anesthesiology and Intensive Care Department no. 1
Russian Federation
Candidate of Medical Sciences, Head of Anesthesiology and Intensive Care Department no. 1
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Review
For citations:
Likhvantsev V.V., Marchenko D.N., Grebenchikov O.A., Ubasev Yu.V., Zabelina T.S., Timoshin S.S. PREVENTION OF HEART FAILURE IN NON-CARDIAC SURGERY WITH THE LOWER EJECTION FRACTION OF LEFT VENTRICULAR: LEVOSIMENDAN OR ANESTHETIC CARDIOPROTECTION? (randomized multi-centered trial). Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2016;13(3):74-79. (In Russ.) https://doi.org/10.21292/2078-5658-2016-13-3-74-79
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