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Nomogram M Prognostic Value for Major Adverse Cardiac and Cerebral Events after Elective Cardiac Surgery with Cardiopulmonary Bypass

https://doi.org/10.21292/2078-5658-2022-19-2-6-13

Abstract

The objective: to evaluate the prognostic value of Nomogram M for major adverse cardiac events (MACE) and major adverse cardiac and cerebral events (MACCE) after elective cardiac surgery with cardiopulmonary bypass.
Subjects and Methods. This is a retrospective cohort study of the Nomogram M prognostic value for MACE and MACCE after elective cardiac surgery with cardiopulmonary bypass. 158 patients were enrolled in the study. The prognostic value was estimated using ROC-analysis.
Results. The frequency of MACE and MACCE during hospitalization made 5.7% (9 of 158 patients) and 6.3% (10 of 158 patients), respectively. AUC Nomogram M for MACE was 0.888 [0.825; 0.950] (p < 0.001). Cut-off value made 12.5 points (sensitivity – 88.89%, specificity – 83.89%). Odd ratio was 41.67 [95% CI 4.98; 348.61] (p < 0.001).
AUC Nomogram M for MACCE was 0.893 [0.834; 0.951] (p < 0.001). Cut-off value made 12.5 points (sensitivity – 90.00%, specificity – 84.46%). Odd ratio was 48.91 [95% CI 5.91; 404.78] (p < 0.001)
Conclusion. Nomogram M has a good prognostic value for the occurrence of MACE and MACCE after elective cardiac surgery with cardiopulmonary bypass. For MACE sensitivity made 88.89%, and specificity – 83.89%. For MACCE sensitivity was 90.00%, specificity – 84.46%.

About the Authors

L. B. Berikashvili
V. A. Negovsky Reanimatology Research Institute; M. F. Vladimirsky Moscow Regional Research and Clinical Institute
Russian Federation

Levan B. Berikashvili, Researcher of Clinical Trial Department

25 Build. 5, Petrovka St., Moscow, 107031



A. N. Kuzovlev
V. A. Negovsky Reanimatology Research Institute
Russian Federation

Artem N. Kuzovlev, Doctor of Medical Sciences, Head

25 Build. 5, Petrovka St., Moscow, 107031



M. Yа. Yadgarov
V. A. Negovsky Reanimatology Research Institute
Russian Federation

Mikhail Ya. Yadgarov, Researcher of Clinical Trial Department

25 Build. 5, Petrovka St., Moscow, 107031



K. K. Kadantseva
V. A. Negovsky Reanimatology Research Institute
Russian Federation

Kristina K. Kadantseva, Researcher of Clinical Trial Department

25 Build. 5, Petrovka St., Moscow, 107031



E. A. Ozhiganova
V. A. Negovsky Reanimatology Research Institute
Russian Federation

Ekaterina A. Ozhiganova, Resident Physician

25 Build. 5, Petrovka St., Moscow, 107031



V. V. Likhvantsev
V. A. Negovsky Reanimatology Research Institute; I. M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Valeriy V. Likhvantsev, Doctor of Medical Sciences, Professor, Deputy Head

25 Build. 5, Petrovka St., Moscow, 107031



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For citations:


Berikashvili L.B., Kuzovlev A.N., Yadgarov M.Y., Kadantseva K.K., Ozhiganova E.A., Likhvantsev V.V. Nomogram M Prognostic Value for Major Adverse Cardiac and Cerebral Events after Elective Cardiac Surgery with Cardiopulmonary Bypass. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2022;19(2):6-13. (In Russ.) https://doi.org/10.21292/2078-5658-2022-19-2-6-13



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