Evaluation of the validity of the nSOFA score in newborns with sepsis
https://doi.org/10.21292/2078-5658-2021-18-2-56-61
Abstract
The objective of the study is to evaluate the discriminative ability of nSOFA in newborns with sepsis.
Subjects: The study was designed as retrospective, observational, and one-center. End points included assessment of the severity as per nSOFA and pSOFA; 28-day survival. 121 patients were enrolled in the study. Microsoft Excel (Graphpad Software, San Diego, California, USA) and MedCalc (v 7.1.0.0; MedCalc Software, Belgium) were used for the analysis.
Results. A study of the discriminative power of the scores showed that both assessment systems had a good model quality. However, nSOFA had a statistically more significant (p < 0.05) area under the ROC curve (0.981± 0.014).
Conclusion. The high value of the discriminative ability of the nSOFA scale indicates the feasibility of its use in patients with sepsis in neonatal intensive care units
About the Authors
P. I. Mironov
Bashkortostan State Medical University
Russian Federation
Russian Federation
Petr I. Mironov, Doctor of Medical Sciences, Professor of Anesthesiology and Intensive Care Department with Professional Development Training
3, Lenina St., Ufa, Bashkortostan Republic, 450008
A. U. Lekmanov
Clinical Surgery Research Institute by Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Andershan U. Lekmanov, Doctor of Medical Sciences, Professor, Chief Researcher of Pediatric Surgery Department, Clinical Surgery Research Institute
1, Ostrovityanova St., Moscow, 117997
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For citations:
Mironov P.I., Lekmanov A.U. Evaluation of the validity of the nSOFA score in newborns with sepsis. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2021;18(2):56-61. (In Russ.) https://doi.org/10.21292/2078-5658-2021-18-2-56-61
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