Viral meningoencephalitis complicated with cerebral edema and coma: efficacy of complex therapy with l-lysin escinate
https://doi.org/10.21292/2078-5658-2019-16-4-77-82
Abstract
The article presents a clinical case of a 14-year-old patient with viral meningoencephalitis complicated with cerebral edema and a brain coma caused by herpes simplex viruses. Comprehensive etiopathogenetic therapy was not sufficiently effective due to the late referral for medical help and the late start of treatment. It has been shown that the use of the L-lysine escinate preparation up to 10 intravenous injections in a single dose of 0.15 mg/kg twice a day, even in the later stages of encephalitis, which has an extremely severe course due to cerebral edema development, is highly effective due to its multifactorial actions.
About the Authors
N. V. Skripchenko
Children’s Research and Clinical Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia; St. Petersburg Pediatric Medical University
Russian Federation
Russian Federation
Natalia V. Skripchenko - Doctor of Medical Sciences, Professor - Deputy Director for Research.
9, Prof. Popova St., St. Petersburg, 197022, Phone: +7 (812) 234‒10‒38
A. A. Vilnitz
Children’s Research and Clinical Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia; St. Petersburg Pediatric Medical University
Russian Federation
Russian Federation
Alla A. Vilnitz - Acting Head of Intensive Care Department, Senior Researcher of Department for Neuroinfection and Organic Pathology of Nervous System.
9, Prof. Popova St., St. Petersburg, 197022, Phone: +7 (812) 234‒19‒01
E. Y. Gorelik
Children’s Research and Clinical Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Evgeniy Yu. Gorelik - Acting Head of Department for Neuroinfection and Organic Pathology of Nervous System.
9, Prof. Popova St., St. Petersburg, 197022, Phone: +7 (812) 234‒19‒01
N. F. Pulman
Children’s Research and Clinical Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Nadezhda F. Pulman - Head of Department for Neuroinfection and Organic Pathology of Nervous System.
9, Prof. Popova St., St. Petersburg, 197022, Phone: +7 (812) 234‒19‒01
A. I. Konev
Children’s Research and Clinical Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia; St. Petersburg Pediatric Medical University
Russian Federation
Russian Federation
Aleksandr I. Konev
9, Prof. Popova St., St. Petersburg, 197022, Phone: +7 (812) 234‒19‒01
E. Yu. Skripchenko
Children’s Research and Clinical Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia; St. Petersburg Pediatric Medical University
Russian Federation
Russian Federation
Elena Yu. Skripchenko - Candidate of Medical Sciences, Senior Researcher of Department for Neuroinfection and Organic Pathology of Nervous System.
9, Prof. Popova St., St. Petersburg, 197022, Phone: +7 (812) 234‒19‒01
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Review
For citations:
Skripchenko N.V., Vilnitz A.A., Gorelik E.Y., Pulman N.F., Konev A.I., Skripchenko E.Yu. Viral meningoencephalitis complicated with cerebral edema and coma: efficacy of complex therapy with l-lysin escinate. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2019;16(4):77-82. (In Russ.) https://doi.org/10.21292/2078-5658-2019-16-4-77-82
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