ACUTE POLYUMERIA SYNDROME INDUCED BY DEXMEDETOMIDINE DURING SPINAL NEUROSURGERY (clinical observation)
https://doi.org/10.21292/2078-5658-2018-15-2-62-67
Abstract
Dexmedetomidine is a high-selective α2-agonist, which is used as an anesthetic component, and it is expected to induce polyuria. Initially, it was mainly used for sedation in emergency wards, and further this medicine got widespread use in anesthesiology. The major positive effect of dexmedetomidine is related to its central sympatholytic action and suppression of the activity of sympathetic nervous system. This medicine also provides a favorable hemodynamic profile. However, it has a number of certain disadvantages. The present clinical study reports development of acute polyuria syndrome due to the administration of dexmedetomidine during spinal neurosurgery.
About the Authors
A. V. Solenkova
Burdenko National Research Center of Neurosurgery
Russian Federation
Russian Federation
Alla V. Solenkova – Candidate of Medical Sciences, Doctor in Anesthesiology and Intensive Care Department
16, 4th Tverskaya-Yamskaya St., Moscow, 125047
O. N. Ivanova
Burdenko National Research Center of Neurosurgery
Russian Federation
Russian Federation
Olga N. Ivanova – Doctor of Anesthesiology and Intensive Care Department
16, 4th Tverskaya-Yamskaya St., Moscow, 125047
A. M. Аrefiev
Burdenko National Research Center of Neurosurgery
Russian Federation
Russian Federation
Alexandr M. Arefiev – Post-Graduate Student, Doctor of Anesthesiology and Intensive Care Department
16, 4th Tverskaya-Yamskaya St., Moscow, 125047
A. Yu. Lubnin
Burdenko National Research Center of Neurosurgery
Russian Federation
Russian Federation
Andrey Yu. Lubnin – Doctor of Medical Sciences, Professor, Head of Anesthesiology and Intensive Care Department
16, 4th Tverskaya-Yamskaya St., Moscow, 125047
N. A. Konovalov
Burdenko National Research Center of Neurosurgery
Russian Federation
Russian Federation
Nikolay A. Konovalov – Correspondent Member of RAS, Doctor of Medical Sciences, Professor, Head of Spinal Neurosurgery Department
16, 4th Tverskaya-Yamskaya St., Moscow, 125047
V. A. Korolishin
Burdenko National Research Center of Neurosurgery
Russian Federation
Russian Federation
Vasiliy A. Korolishin – Neurosurgeon, Researcher of Spinal Neurosurgery Department
16, 4th Tverskaya-Yamskaya St., Moscow, 125047
S. Yu. Timonin
Burdenko National Research Center of Neurosurgery
Russian Federation
Russian Federation
Stanislav Yu. Timonin – Resident of Spinal Neurosurgery Department
16, 4th Tverskaya-Yamskaya St., Moscow, 125047
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Review
For citations:
Solenkova A.V., Ivanova O.N., Аrefiev A.M., Lubnin A.Yu., Konovalov N.A., Korolishin V.A., Timonin S.Yu. ACUTE POLYUMERIA SYNDROME INDUCED BY DEXMEDETOMIDINE DURING SPINAL NEUROSURGERY (clinical observation). Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2018;15(2):62-67. (In Russ.) https://doi.org/10.21292/2078-5658-2018-15-2-62-67
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