EXPERIENCE OF USING DEXMEDETOMIDINE FOR DRUG SEDATION IN INTRALUMINAL ENDOSCOPIC SURGERY
https://doi.org/10.21292/2078-5658-2016-13-6-40-47
Abstract
Goal of the study: to evaluate the possibility of using dexmedetomidine for drug sedation when performing intraluminal endoscopic surgery (ILES). Materials and methods. 136 cases of dexmedetomidine used were analyzed in 100 patients at the age of 58.0 ± 1.5 years old (Me = 59, Min = 22, Max = 87) during the first and repeated video-assisted bronchoscopies, esophagogastroscopies, duodenoscopies and colonoscopies lasting for 73 ± 3 min. (Me = 65, Min = 15, Max = 330). Results. Sole use of dexmedetomidine was effective only in short-term ILES causing minimal trauma. If ILES lasts longer and causes bigger trauma dexmedetomidine is to be combined with nefopam, fentanyl, trimeperidin, propofol, and ketamine. Combined use of dexmedetomidine resulted in the reduction of doses of the drugs, provided opportunity to manage the depth of sedation without depression of spontaneous respiration, post-operative and post-procedure agitation, algidity, nausea and vomit. Conclusion. Dexmedetomidine can be considered as the drug of choice for sedation in ILES.
About the Authors
M. G. Kovalev
Pavlov First Saint Petersburg State Medical University, St. Petersburg
Russian Federation
Candidate of Medical Sciences, Associate Professor of Anesthesiology and Intensive Care Department
Russian Federation
Candidate of Medical Sciences, Associate Professor of Anesthesiology and Intensive Care Department
I. V. Shlyk
Pavlov First Saint Petersburg State Medical University, St. Petersburg
Russian Federation
Doctor of Medical Sciences, Deputy Head Doctor for Anesthesiology and Intensive Care of the Clinic, Deputy Head of Research Clinical Center of Anesthesiology and Intensive Care, Professor of Anesthesiology and Intensive Care Department
Russian Federation
Doctor of Medical Sciences, Deputy Head Doctor for Anesthesiology and Intensive Care of the Clinic, Deputy Head of Research Clinical Center of Anesthesiology and Intensive Care, Professor of Anesthesiology and Intensive Care Department
Yu. S. Polushin
Pavlov First Saint Petersburg State Medical University, St. Petersburg
Russian Federation
Doctor of Medical Sciences, Professor, Pro-Rector for Research, Head of Research Clinical Center of Anesthesiology and Intensive Care, Head of Anesthesiology and Intensive Care Department
Russian Federation
Doctor of Medical Sciences, Professor, Pro-Rector for Research, Head of Research Clinical Center of Anesthesiology and Intensive Care, Head of Anesthesiology and Intensive Care Department
A. L. Akopov
Pavlov First Saint Petersburg State Medical University, St. Petersburg
Russian Federation
Doctor of Medical Sciences, Professor, Head of Thoracic Surgery Department of Surgery and Emergency Care Research Institute
Russian Federation
Doctor of Medical Sciences, Professor, Head of Thoracic Surgery Department of Surgery and Emergency Care Research Institute
A. A. Smirnov
Pavlov First Saint Petersburg State Medical University, St. Petersburg
Russian Federation
Candidate of Medical Sciences, Head of Endoscopy Department of Research Institute of Surgery and Emergency Care
Russian Federation
Candidate of Medical Sciences, Head of Endoscopy Department of Research Institute of Surgery and Emergency Care
A. A. Rusanov
Pavlov First Saint Petersburg State Medical University, St. Petersburg
Russian Federation
Candidate of Medical Sciences, Researcher of Thoracic Surgery Department, Group of Intraluminal Endoscopy, Research Institute of Surgery and Emergency Care
Russian Federation
Candidate of Medical Sciences, Researcher of Thoracic Surgery Department, Group of Intraluminal Endoscopy, Research Institute of Surgery and Emergency Care
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Review
For citations:
Kovalev M.G., Shlyk I.V., Polushin Yu.S., Akopov A.L., Smirnov A.A., Rusanov A.A. EXPERIENCE OF USING DEXMEDETOMIDINE FOR DRUG SEDATION IN INTRALUMINAL ENDOSCOPIC SURGERY. Messenger of ANESTHESIOLOGY AND RESUSCITATION. 2016;13(6):40-47. (In Russ.) https://doi.org/10.21292/2078-5658-2016-13-6-40-47
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